As others have said, it is all a matter of personal preference, and also what type of music you play. Do you need the range of a larger instrument? My four-decade journey with the accordion has been to progressively smaller instruments.
Personally, I see no point to having a bigger instrument than is necessary for the styles of music one plays. Some genres may require a full-sized accordion, but I play mostly folk music. I started out with full size 4 reed piano accordions, but after several years decided that, in my opinion, they were overkill and looked a little ridiculous in a folk band. I am not being critical of many excellent folk musicians who play these instruments, just saying for me it made no sense to carry around that size and weight. I then moved to a 3 reed/72 bass PA, and eventually switched to a 3 reed/4 row/60-bass LMM CBA. I still have it, but don't use it much anymore.
I now play a very compact, 2 reed/3 row MM CBA with a Darwin 24-bass system (fully chromatic, but only open chords). It is less than 10 lbs. I like it a lot, and it makes my other medium-sized CBA seem like a monster. I do miss having the sound options of an LMM instrument, but I have learned to be satisfied with the one light musette sound. I have found it to be easier to play and louder than my larger CBA, and I think the open chord bass sounds better in a folk music setting.
Substituting a Darwin bass for a Stradella can reduce the size and weight, but I don't think this is currently offered on small piano accordions. If you are a folk musician who plays the PA, look up some YouTube videos of Scottish accordionist Sandy Brechin. He is fantastic playing a small Hohner 48-bass "student" PA.